When Democratic presidential nominee Hillary Clinton debates Donald Trump on Wednesday night, she should face a number of questions she has managed to avoid in previous debates.

Chris Wallace of Fox News will be the third debate moderator at the contest in Las Vegas. It will fall to him to ensure Clinton is asked the relevant, crucial questions about her record, vision for the nation, and scandals she has heretofore dodged.

“What’s the ideal level of immigration into the United States?”

One of the biggest questions that has flown stealthily under the radar is not about the private email server she ran in her basement; it’s not about her health or her handling of the terror attack on the U.S. consulate in Benghazi.

It’s about Russian uranium.

Speaking on his radio show on Monday, talk show giant Rush Limbaugh indicated it would be his first question.

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“Why did you let a Russian company purchase one half of the United States uranium reserves in coordination [the Clinton Foundation]?” Limbaugh queried — rhetorically, of course.

The Russian company’s takeover of U.S. uranium sources has infuriated many Clinton critics. The deal was approved by several government agencies, including the State Department under then-Secretary of State Hillary Clinton.

But PolitiFact said the State Department “didn’t act unilaterally. State was one of nine government agencies, not to mention independent federal and state nuclear regulators, that had to sign off on the deal.” That’s a weak argument. The State Department and the White House schemed to stop the Keystone XL pipeline crossing into the United States — and they did.

PolitiFact also argued the donations to the Clinton Foundation were made two years before the uranium deal. Still, Clinton should have to answer the question and not rely on the media to answer for her.

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Another question Clinton should have to answer is one usually aimed at Republican Donald Trump.

Trump is usually put on the defensive for his positions on illegal immigration, a border wall along the Mexican border, and “extreme vetting” for immigrants from troubled parts of the world.

But Clinton has not really had to spell out any of the specifics of her radical immigration and refugee plans at any of the first two debates. Instead, she has enjoyed letting Trump twist in the wind for some of the statements he has made on immigration.

That should change in the final debate.

Tucker Carlson, a Fox News contributor and editor-in-chief of The Daily Caller, would pose a simple question: “What’s the ideal level of immigration into the United States?”

Carlson has said before that large-scale immigration can depress wages. He has also said a magic wave of the amnesty wand — giving more than 11 million illegal aliens a permanent residency with the right to work — will definitely depress wages in the labor market.

Clinton has not been pressed on the issue at the first two debates.

Dan Gainor, vice president of Business and Culture at the Media Research Center, says Clinton should also have to answer for her leaked remarks about immigration.

“She obviously needs to answer for her secret statements calling for open borders and merging the U.S. into a common market,” says Gainor. “That’s essentially the destruction of America and I’m pretty sure a lot of voters would care. The media have suppressed it big time.”

Abortion is usually an issue that left-leaning journalists love to use — against Republicans. Questions about abortion during a TV interview ended U.S. Rep. Todd Akin’s Senate run in 2012.

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And a question at an Indiana debate for the U.S Senate that same year threw off State Treasurer Richard Mourdock, who veered poorly when he explained why he opposed abortion even in the case of rape.

But Democrats need to be asked about the issue too. Dave Andrusko, editor of National Right to Life News, posed this question on LifeNews.com: “There are 80-90 million people viewing this first presidential debate, Secretary Clinton. Do you still stick by what you told Chuck Todd of “Meet the Press,” that ‘the unborn person doesn’t have constitutional rights,’ including (when asked by Paula Paris of The View) ‘on its due date, just hours before delivery?'”

Clinton’s view on abortion may be beyond that of even pro-choice mainstream voters. She should be asked about it. She should be asked whether she supports the 20-week nationwide ban on abortion that has been floated in Congress. Twenty weeks is when some scientific consensus agrees a baby can feel pain and polls have consistently shown a wide majority of Americans are in favor of a ban at that stage of a pregnancy.

Richard Grenell, a former assistant to several U.S. ambassadors to the United Nations, says terrorism should be a subject, but not regarding ISIS: “Why, when given the chance, did you decide against putting Boko Haram on the terror list?”

But perhaps the most potent issue is the email question. But it isn’t about the server or any of the fine points about what Clinton did or didn’t do. It isn’t about an apology — she has offered one.

It isn’t about trustworthiness. On Tuesday, Fox News released a poll showing that 67 percent of voters think she is lying about the private server issue.

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The press has her on record, many times, twisting the truth about not receiving or sending classified materials on this private server. Asking her a question about this will just invite more lies, more deflection, and more jargon that she will use as a smokescreen.

What Clinton should be asked is whether she knew of a “quid pro quo” offered by her ally at Foggy Bottom, Under Secretary of State Patrick Kennedy. According to the FBI, Kennedy and an FBI agent discussed possibly illegal favors to be given to the FBI if emails were exempted from a Freedom of Information Act request in mid-2015.

The email in question would not be called “secret” and thus would not be used to embarrass Clinton. But the email would also be buried in the State Department basement, according to the FBI document on the email investigation released Monday.

Wallace has many good questions to ask Clinton. Unlike Lester Holt, the NBC News anchor and debate moderator from the first debate, Wallace should ask tough questions of both candidates — not just Trump.